解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Karyotypes of two bark-lice species Amphipsocus japonicus End. and Dasypsocus japonicus End. (Amphipsocidae, Psocomorpha, Psocoptera) were studied for the first time. D. japonicus displayed 2n = 16 (14 + XX/X0). The XX/X0 sex chromosome system observed in this species is characteristic of the order Psocoptera. A. japo...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::The presence of P. tetraurelia was found in the pond in "The Palm-House" greenhouse. ...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::Little is known about the physiological events occurring in the chicken ovary during a pause in laying, therefore the aim of the present study was to examine changes in sex steroid concentration in the follicle wall and blood plasma during cessation of egg laying. The experiment was performed on laying Isa Brown hens....
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::The distribution of DSIP-IR cell bodies and fibers was investigated in the normal human hypothalamus during the first postnatal year using the indirect immunofluorescence technique. The analysis of the immunohistochemical patterns obtained in the seven cases analyzed showed regional differences in the localization of ...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::The influence of Cd (1 mg/rat CdCl2 i.p.) and/or gamma radiation (6 Gy) on RNA and DNA content and/or concentration in the intact kidney and hypertrophic kidney (on the 44th hour after UN) and in other slowly and quickly proliferating organs was studied. The period between administration of Cd and Ir in the group with...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::Microorganisms present in water samples from various industrial effluents were analysed for their resistance to lead, chromium, and cadmium. The ability of these microorganisms to grow on or metabolize toxic hydrocarbons and pesticides was also checked. Microorganisms in samples from the steel and tanning industries w...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::PWD/Ph and PWK/Ph (abbreviated PW*) are highly inbred mouse strains (F66 and F70) derived from wild mice of Mus musculus musculus subspecies. When compared with laboratory inbred strains, they display a plethora of differences in many complex phenotypes such as body weight, fat distribution pattern, blood levels of in...
journal_title:Folia biologica
pub_type: 杂志文章,评审
doi:
更新日期:2000-01-01 00:00:00
abstract::The occurrence rates of class I HLA alleles were investigated in a sample of the Slovak population by a PCR-SSP method. The frequencies of HLA-A alleles ranged from 0.00 for A*4301 to 0.2798 for A*0201-22; the frequencies of HLA-B alleles ranged from 0.00 for B 4601,B* 4801-3, B*5901,B* 7301, and B* 8101 to 0.1101 for...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::The authors investigated the carotenoid content in different parts of Anguilla anguilla (L.) undertaking spawning migration, in spring, summer and autumn. By means of column and thin-layer chromatography, the following carotenoids were found to be present: beta-carotene, epsilon-carotene, beta-cryptoxanthin, neothxant...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::The aim of this study was to register the zooplanktonic organisms in water bodies in the Botanical Garden of the Jagiellonian University in Kraków, especially from the point of view of the occurrence of species of the Paramecium aurelia complex. In one pond, artificially constructed, the presence of P. tetraurelia was...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::The teratogenic effect of RA was found to be significantly influenced both by genetic background and by the genotype of malformation mutation Lx. The presence of the Lx mutation and BN genetic background strongly increases the teratogenic effect of RA. On the contrary, the SHR genetic background was shown to protect f...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::Genome scan and metabolic profile of the PD/Cub rat inbred strain in comparison with SHR and BN strains is presented. The PD/Cub strain has been bred by brother sister mating for more than 60 generations since 1969. Its highly inbred status has been confirmed by PCR genotyping with more than 170 microsatellite markers...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::Intradermal administration of concanavalin A, a potent T-cell mitogen, into an ear lap resulted in activation of chondrogenesis and stimulation of epidermis proliferation. This proliferation is sometimes invasive in character (pearls and epidermal nests form in the underlying connective tissue) but never turns into tr...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::Steroidogenic key enzymes, i.e. delta 5-3 beta and 17 beta-hydroxysteroid dehydrogenase (delta 5-3 beta and 17 beta-HSD) activities, in the testis and Bidder's organ of the toad were inhibited and ascorbic acid synthesis in these organs was decreased by a wide range of lithium concentration in in vitro study. A signif...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::The distribution of SSPs representing AgNORs was studied in human as well as rat proerythroblasts to provide information on the distribution of these nucleolar components in highly immature and proliferating non-neoplastic cells. The distribution of SSPs was asymmetric and most of the cells contained one nucleolus whi...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::Endogenous lectins are proteins/glycoproteins which selectively recognize distinct saccharide ligands and are different from immunoglobulins and carbohydrate-utilizing enzymes. Expression of these molecules can be detected immunohistochemically using nonblocking monoclonal antibodies (A1D6: anti-galectin-3, MR-15-2-2:...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::Retinoic acid (RA) and phorbol esters are important regulators of cellular proliferation and differentiation processes which are capable of arresting growth and inducing differentiation of various leukemic cells. We have studied and compared the effects of these agents on the line of v-myb oncogene-transformed chicken...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::Heparin-binding proteins BHB 2-BHB 5 were purified from boar seminal plasma by affinity chromatography on a heparin-polyacrylamide column and reversed phase HPLC. Three of the proteins, BHB 3-BHB 5, were found to be identical to spermadhesins AQN 1-AQN 3 isolated from boar spermatozoa. The lectin-like properties of th...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::The transport and localization of env-proteins of ts1 virus (a paralytogenic temperature-sensitive mutant of Moloney murine leukemia virus) in infected cells of the TB cell line have been studied at the ultrastructural level. It was found that the envelope precursor polyprotein gPr80-env of ts1 was inefficiently trans...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::In Dictyostelium discoideum inactivation of developmentally regulated genes via homologous recombination has become an important tool in studying systematically the entire developmental program of this model organism. The Dictyostelium genome is very A/T-rich,which presents obstacles to the preparation of knockout con...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::Studies were carried out in adult male Swiss mice to determine whether different haematological parameters like total counts of red and white blood cells, differential counts of white blood cells, haematocrit value and blood haemoglobin level were affected by the synthetic opioid analgesic, buprenorphine, which has cu...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::Evaluation of the degree of sexual maturation was performed in male mice of two selected lines differing in respect of body weight. Four developmental stages were distinguished: (1) loosening of the skin between the urinary papilla and the anus, (2) projection of the scrotum, (3) descent of the testes to the scrotum, ...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::The antiphlogistic Ibuprofen incorporated in liposomes caused a decrease of the inflammatory edema induced by Carrageenan in the distal part of the rat's hind leg after both the intramuscular and percutaneous administration. The antiphlogistic effect of free Ibuprofen in the cream was weaker. Intramuscular administrat...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::Two different modifications of CTLL techniques for IL-2 detection, the routine 3II-thymidine incorporation assay and the colorimetric MTT method, were compared. The reproducible results of the studies of supernatants from in vitro propagated transfected cells were obtained. The employed methods appeared to be comparab...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::A hyperthermic shock (43 degrees C/30 min) enhances in somite stages of the chick embryo development the activity of the caudal morphogenetic system, manifested by intensive growth of the embryonic trunk. The exposure also induced the synthesis of heat shock proteins (HSP 70). A single administration of a bioflavonoid...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::It has not been established whether seric antiamebic antibodies are produced after local presence of amebas, or only after they invade the tissues. Therefore, the purpose of this work was to determine if mucosal immunization with glutaraldehyde-fixed trophozoites (GFT) could induce seric anti-amebic antibody responses...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::The localization and extent of metastasis determined the prognosis of breast cancer in a decisive manner. Thereby axillary lymph node involvement represents one of the most important prognostic indicators. The estradiol receptor status is also attributed some prognostic importance. There might therefore be relations b...
journal_title:Folia biologica
pub_type: 杂志文章,评审
doi:
更新日期:1996-01-01 00:00:00
abstract::This review first summarizes the different strategies of gene therapy of cancer and then focuses on the immunological approach. Several studies in animal models with cytokine gene-transduced tumor cells indicate that local cytokine release usually results in tumor growth inhibition. Moreover, in a number of cases vacc...
journal_title:Folia biologica
pub_type: 杂志文章,评审
doi:
更新日期:1996-01-01 00:00:00
abstract::The frequency of micronucleated polychromatic erythrocytes (MNPCEs) in the mouse peripheral blood was assessed after WR-2721 (S-2-/3-aminopropylamino/ethyl phosphorothioic acid) application and X-irradiation. A genotoxic effect was demonstrated for X-rays and WR-2721, as well as a protective effect of the thiol drug a...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::The functional capacity of human T cells to passively transfer delayed hypersensitivity (DH) was analysed in severe combined immunodeficiency (SCID) mice. The tissue distribution of human peripheral blood lymphocytes (PBL) was analysed by 51chromium labelling 1 and 24 h after intravenous cell injection. Labelled PBL f...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::We detected a strong correlation between the constitutive expression of IL-1 alpha and reduced tumorigenicity, using fibrosarcomas which produce the cytokine spontaneously (as an aberration of the transformation process) or upon gene transfer. In fibroblasts intracellular or membrane-associated IL-1 alpha is expressed...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Molecular dynamics simulation was used to identify the conformational alterations in the Fab fragment (Kol), driven by heating at 300, 320, and 340 K. Comparison of heat-modified VH,CH1 and VL,CL domain structures with the corresponding crystal conformations revealed specific differences, most definitely expressed in ...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Severe graft-versus-host disease (GVHD) developed following intravenous administration of parental BN.lx lymphoid cells into (SHR x BN.lx)F1 animals. Clinical symptoms, including foot-pad hyperemia, slobbering, melaena, progressive weight loss leading to death within 3 to 4 weeks, can be completely abrogated by 8 inje...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Measuring absorption spectra of conjugated dienes it has been shown that microwave radiation with a frequency of 2.54 GHz induces lipid peroxidation of phosphatidylcholine liposomes. The relationship with the previously observed microwave-enhanced liposome permeability is discussed. ...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::So far, more than 17,000 embryos have been frozen in the repository of the cryobank in the Institute of Molecular Genetics. The freezing of embryos from more than 20 inbred, congenic and mutant strains has been completed. For purposes of embryo banking, a modified two-step method was used. The first step includes slow...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::The clinical observations of increased risk of bacterial infection in patients with severe hypothyroidism motivated investigations of the biological function of neutrophils in peripheral blood of 30 women with primary hypothyroidism. The following functions of neutrophils were examined: phagocytosis, adherence to fibe...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::A sublethal dose of Karate administered to rabbits produced a significant increase in the total erythrocyte count and packed cell volume after 15 days of administration, though no significant change was observed after 30 days. The transaminases (glutamate oxaloacetate transaminase, GOT; glutamate pyruvate transaminase...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::The aim of the experiments was to evaluate the effect of administration of cysteine, methionine, thiocystine, and thiosulphate upon the activity of mercaptopyruvate sulphurtransferase (MPST) and rhodanese in mouse liver. It was found that rhodanese activity increased following thiocystine and methionine administration...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::The process of nucleologenesis was examined in preimplantation bovine embryos by using ethanolic phosphotungstic acid (E-PTA) at the electron microscopic level. E-PTA binds basic lysine-rich proteins and thus makes possible detection of their localization and distribution. In blastomere nuclei of 2-, 4- and early 8-ce...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::Joint disease, ankylosing enthesopathy (ANKENT) of the ankle, occurs naturally in mice. ANKENT depends on the genetical constitution, sex, and age, and its frequency varies among inbred strains of normal mice. We found the highest frequency of ANKENT in B10.BR (H-2k) males. The H-2k haplotype appears to be a relative ...
journal_title:Folia biologica
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00